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Inference from SNP array data through GWAS has shown that approximately one-third to two-thirds of the pedigree heritability can be captured from common SNPs. For psychiatric disorders, estimates of SNP-heritability are typically less than 50% of the estimates of pedigree heritability. One hypothesis of the difference between these estimates is that low frequency and rare variants are not sufficiently tagged by common genotyped and imputed variants. If remaining genetic variance can be captured from whole-genome-sequence (WGS) data then this has implications of gene and gene variant discovery and for polygenic prediction. We will show results from analyses on WGS data on more than 20,000 samples on the ‘model’ traits height and BMI.
Recorded: 02/02/2005
CERIAS Security Seminar at Purdue University
Obfuscated Databases: Definitions and Constructions
Vitaly Shmatikov, University of Texas at Austin
I will present some new definitions and constructions for privacy in
large databases. In contrast to conventional privacy mechanisms that aim
to prevent any access to individual records, our techniques are designed
to prevent indiscriminate harvesting of information while enabling some
forms of legitimate access.
We start with a simple construction for an obfuscated database that is
provably indistinguishable from a black-box lookup oracle (in the random
oracle model). Some attributes of the database are designated as "key,"
the rest as "data." The database behaves as a lookup oracle if, for any
record, it is infeasible to extract the data fields without specifying
the key fields, yet, given the values of the key fields, it is easy to
retrieve the corresponding data fields.
We then generalize our constructions to a larger class of queries, and
achieve a privacy property we call "group privacy." It ensures that
users can retrieve individual records or small subsets of records from
the database by identifying them precisely. The database is obfuscated
in such a way that queries returning a large subset of records are
computationally infeasible.
This is joint work with Arvind Narayanan.
Vitaly Shmatikov is an assistant professor in the Department of Computer
Sciences at the University of Texas at Austin. Prior to joining UT,
he worked as a computer scientist at SRI International. Vitaly\'s
research focuses on tools and formal methods for automated analysis and
verification of secure systems, as well as various aspects of anonymity
and privacy. Vitaly received his PhD in 2000 from Stanford University,
with thesis on \"Finite-State Analysis of Security Protocols.\"
(Visit: www.cerias.purude.edu)
If you record an awesome shot with a bow and upload it to youtube, send me the link and you could win a prize!
"How do I get in the Castrum (Fort)?" - There are little towers on each wall, go to these with a friend, and jump on them, you can get on the walls and open the door for anyone else who wants to get in!
L - Leaderboard
G - Inventory
Q - Shield Forward
R - Shield Up
F - Shield Down
T - Taunt with Sword
Game Passes: Click "Redeem Pases" in the top left to redeem specified items.
Crafting: Go to a crafting bench located most commonly in the small huts, press the arrow to forge an item and it will appear on the bench, not your inventory!
Corrupted Data or Other Issue? - Press "Purge Data" and you will start as the default character with an axe and a pickaxe.
Visit this place at http://www.roblox.com/Roman-Pa....rthia-Bows-place?id=
For more games visit http://www.roblox.com
"How do I get in the Castrum (Fort)?" - There are little towers on each wall, go to these with a friend, and jump on them, you can get on the walls and open the door for anyone else who wants to get in!
L - Leaderboard
G - Inventory
Q - Shield Forward
R - Shield Up
F - Shield Down
T - Taunt with Sword
Game Passes: Click "Redeem Pases" in the top left to redeem specified items.
Crafting: Go to a crafting bench located most commonly in the small huts, press the arrow to forge an item and it will appear on the bench, not your inventory!
Corrupted Data or Other Issue? - Press "Purge Data" and you will start as the default character with an axe and a pickaxe.
Visit this place at http://www.roblox.com/Roman-Pa....rthia-NEW-MAP-26-NEW
For more games visit http://www.roblox.com
If you record an awesome shot with a bow and upload it to youtube, send me the link and you could win a prize!
"How do I get in the Castrum (Fort)?" - There are little towers on each wall, go to these with a friend, and jump on them, you can get on the walls and open the door for anyone else who wants to get in!
L - Leaderboard
G - Inventory
Q - Shield Forward
R - Shield Up
F - Shield Down
T - Taunt with Sword
Game Passes: Click "Redeem Pases" in the top left to redeem specified items.
Crafting: Go to a crafting bench located most commonly in the small huts, press the arrow to forge an item and it will appear on the bench, not your inventory!
Corrupted Data or Other Issue? - Press "Purge Data" and you will start as the default character with an axe and a pickaxe.
Visit this place at http://www.roblox.com/Roman-Pa....rthia-Bows-place?id=
For more games visit http://www.roblox.com
Join Rome for benefits! http://www.roblox.com/groups/group.aspx?gid=954556
CRAFTED ITEMS SPAWN ON THE BENCH, YOU HAVE TO PICK THEM UP!
Most of the time you can't share siege weapons meaning only you can operate it. [This will be changed next update]
If you record an awesome shot with a bow and upload it to youtube, send me the link and you could win a prize!
"How do I get in the Castrum (Fort)?" - There are little towers on each wall, go to these with a friend, and jump on them, you can get on the walls and open the door for anyone else who wants to get in!
L - Leaderboard
G - Inventory
Q - Shield Forward
R - Shield Up
F - Shield Down
T - Taunt with Sword
Game Passes: Click "Redeem Pases" in the top left to redeem specified items.
Crafting: Go to a crafting bench located most commonly in the small huts, press the arrow to forge an item and it will appear on the bench, not your inventory!
Corrupted Data or Other Issue? - Press "Purge Data" and you will start
Visit this place at http://www.roblox.com/Parthian....-Warzone-Siege-Bows-
For more games visit http://www.roblox.com
If you record an awesome shot with a bow and upload it to youtube, send me the link and you could win a prize!
"How do I get in the Castrum (Fort)?" - There are little towers on each wall, go to these with a friend, and jump on them, you can get on the walls and open the door for anyone else who wants to get in!
L - Leaderboard
G - Inventory
Q - Shield Forward
R - Shield Up
F - Shield Down
T - Taunt with Sword
Game Passes: Click "Redeem Pases" in the top left to redeem specified items.
Crafting: Go to a crafting bench located most commonly in the small huts, press the arrow to forge an item and it will appear on the bench, not your inventory!
Corrupted Data or Other Issue? - Press "Purge Data" and you will start as the default character with an axe and a pickaxe.
Visit this place at http://www.roblox.com/Roman-Pa....rthia-Bows-place?id=
For more games visit http://www.roblox.com
Remote sensing is a key method in bridging the gap between local observations and spatially comprehensive estimates of environmental variables. For such spatial or spatio-temporal predictions, machine learning algorithms have shown to be a promising tool to identify nonlinear patterns between locally measured and remotely sensed variables. While easy access to user-friendly machine learning libraries fosters their use in environmental sciences, the application of these methods is far from trivial. This holds especially true for spatio-temporal since its dependencies in space and time bear the risk of overfitting and considerable misinterpretation of the model performance.
In this introductory lecture I will introduce the idea of using machine-learning for the (remote sensing based) monitoring of the environment and how they can be applied in R via the caret package. In this context error assessment is a crucial topic and I will show the importance of "target-oriented" spatial cross-validation strategies when working with spatio-temporal data to avoid an overoptimistic view on model performances. As spatio-temporal machine-learning models are highly prone to overfitting caused by misleading predictor variables, I will introduce a forward feature selection method that works in conjunction with target-oriented cross-validation from the CAST package.
In summary this talk aims at showing how "basic" spatial machine-learning tasks can be performed in R, but also what needs to be considered for more complex spatio-temporal prediction tasks in order to produce scientifically valuable results. Based on this talk, we will go into a practical session on Tuesday, where machine-learning algorithms will be applied to two different spatial and spatio-temporal prediction tasks.
Slides: https://github.com/HannaMeyer/....Geostat2018/tree/mas
2/27/2012 - V: 3.1.2 - Zombies can no longer spawn kill, and the "taking damage from shooting" glitch is now fixed. I'm sure of it this time. ;P
Visit this place at http://www.roblox.com/Survival....-Apocalypse-place?id
For more games visit http://www.roblox.com
2/27/2012 - V: 3.1.2 - Zombies can no longer spawn kill, and the "taking damage from shooting" glitch is now fixed. I'm sure of it this time. ;P
Visit this place at http://www.roblox.com/Survival....-Apocalypse-place?id
For more games visit http://www.roblox.com
Déterminée et sensuelle, elle a fait du cuir et du denim ses secondes peaux... après les chromes de sa moto.
Photographie et réalisation : Achraf Akkar
Stylisme : Sarah Nadjar
Coiffure et Make up : Marian Filali
Mannequin : Marion Piveteau
Pour FDM / Femmes du Maroc magazine - Novembre 2015
Try out this game: http://www.roblox.com/Modern-A....ssault-place?id=7125
2/27/2012 - V: 3.1.2 - Zombies can no longer spawn kill, and the "taking damage from shooting" glitch is now fixed. I'm sure of it this time. ;P
Visit this place at http://www.roblox.com/Survival....-Apocalypse-place?id
For more games visit http://www.roblox.com
Try out this game: http://www.roblox.com/Modern-A....ssault-place?id=7125
2/27/2012 - V: 3.1.2 - Zombies can no longer spawn kill, and the "taking damage from shooting" glitch is now fixed. I'm sure of it this time. ;P
Visit this place at http://www.roblox.com/Survival....-Apocalypse-place?id
For more games visit http://www.roblox.com
2/27/2012 - V: 3.1.2 - Zombies can no longer spawn kill, and the "taking damage from shooting" glitch is now fixed. I'm sure of it this time. ;P
Visit this place at http://www.roblox.com/Survival....-Apocalypse-place?id
For more games visit http://www.roblox.com
2/27/2012 - V: 3.1.2 - Zombies can no longer spawn kill, and the "taking damage from shooting" glitch is now fixed. I'm sure of it this time. ;P
Visit this place at http://www.roblox.com/Survival....-Apocalypse-place?id
For more games visit http://www.roblox.com
Abonnez vous !
https://goo.gl/J38CUh
Nicki Minaj fait la couverture du magazine Nylon en avril !Et c'est sur son Instagram que la chanteuse américaine a diffusé les vidéos des coulisses de son shooting mode so sexy ! On découvre Nicki avec des petites tenues très colorées qui mettent en valeur ses formes généreuses :- Avec des gants U.S en strass et paillettes et un t-shirt Mickey ouvert sur les côtés. Une série de photos très provoc' qui risque de vous mettre chaos !
Même Nicki n'en revient pas : " J'adore les photos de cette tenue. Elles sont incroyables. Je valide à 100% ! " - Un top crop et une jupe très colorés style année 90- Avec une perruque au carré blond peroxydée et une veste rose pastel parsemée de clous argentés. -Avec une veste où des coquillages roses et blancs sont incrustés... Un de ces clichés a été choisi pour faire la une du magazine Nylon.
Découvrez aussi Nicki vêtue d'un simple soutien-gorge noire entrain de grimacer .. Un shooting qui vaut le coup d'oeil et que les followers de la chanteuse semblent adorer : " Quelle bombe ! Félicitations Nicki pour ce très beau shooting ! ", "C'est extra, cette fille est d'une beauté incroyable, je t'adore les cheveux courts ! ", " Hâte de te voir sur scène, tu vas encore m'éblouir par ta beauté. Ce shooting confirme tout ce que je pense : exquise ! " Vite découvrez en vidéo : "Nicki Minaj : les coulisses de son shooting so sexy pour le magazine Nylon" et réagissez !
![Supermensch: The Legend of Shep Gordon 2014 Official Trailer [HD 1080p]](https://i.ytimg.com/vi/EcLaOBauBhk/maxresdefault.jpg)
In 1991, music manager Shep Gordon held Mike Myers over a barrel a few weeks before shooting "Waynes World" regarding an Alice Cooper song Myers wanted to use in the film. They have been close friends ever since. 22 years later, the story of Gordons legendary life in the uber-fast lane is now told in Myers directorial debut. And this time its Myers who has Gordon over a barrel. Capitalist, protector, hedonist, pioneer, showman, shaman... SUPERMENSCH. Shep Gordon is the consummate Hollywood insider. Though he isnt a household name, Gordon has become a beacon in the industry, beloved by the countless stars he has encountered throughout his storied career. Gordons unlikely story will be told by those who know him best, his pals, including Alice Cooper, Michael Douglas, Sylvester Stallone, Anne Murray, Willie Nelson, Emeril Lagasse and more.FacebookTwitterDirector Mike Myers
Genre Documentary
Run Time 1 hour 24 minutes Copyright to Production company
